first-pass effect
Medical term Basic Pharmacology
Metabolism of an oral drug before it reaches its site of action, which reduces the amount of active drug.
Sources
- Pharmacology for Nurses, Chapter 2 Key Terms · OpenStax
Related terms
- metabolismThe sum of all chemical reactions in the body.
- duration of actionHow long a drug keeps working.
- elixirA liquid medication form with sugar, flavoring and alcohol.
- enteralA route through the digestive tract, such as by mouth or feeding tube.
- excretionRemoval of a drug from the body, mainly through the kidneys.
- formularyThe list of drugs a plan covers, often grouped into cost tiers.
- generic nameThe official, nonproprietary name of a drug, such as ibuprofen.
- half-lifeThe time it takes for the drug level in the blood to drop by half.
- indicationThe reason a drug is prescribed.